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Using Toujeo® Here's How.

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KATHY: Hi, my name is Kathy, and I’m a Certified Diabetes Educator who works with patients taking Toujeo® (insulin glargine injection) 300 Units per milliliter.

GAIL: And I’m Gail. My doctor prescribed me Toujeo® to help manage my type 2 diabetes.

KATHY: Today, we’re going to show you how to use and store your Toujeo® SoloStar® pen.

Learning how to properly use your Toujeo® SoloStar® pen can help get you off to a good start on your Toujeo® treatment.

Prescription Toujeo® is a long-acting insulin used to control blood sugar in adults with diabetes mellitus.

  • Toujeo® contains 3 times as much insulin in 1 milliliter as standard insulin (100 Units per milliliter)
  • Toujeo® is not for use to treat diabetic ketoacidosis
  • Toujeo® should not be used in children

GAIL: Before we start, let’s take a look at the pen. I’ve been using the Toujeo® SoloStar® pen for some time now, and it has features that I really like.

It uses a small, thin needle...

...It has push-button injection, with a hold time of only 5 seconds..., the dosing window is large, and clearly displays the dosage amount. It helps me check that I’ve dialed in my correct dose.

KATHY: Remember, don’t share needles or insulin pens with others, even if the needle has been changed. And don’t reuse needles.

In this video, Gail and I will be taking you through each of the 6 steps for using your Toujeo® SoloStar® pen:

  • Checking your pen
  • Attaching a new needle
  • Performing a safety test
  • Selecting the dose
  • Injecting your dose
  • And removing the needle

Remember to talk with your healthcare provider about how to inject before you begin using your pen. Review all of the instructions before using your pen. If you do not follow all of these instructions, you may get too much or too little insulin.

Step 1: Check your pen

GAIL: If you’re going to be using a new Toujeo® SoloStar® pen, take it out of the refrigerator at least 1 hour before use to let it warm up. I’ve found that cold insulin can be painful to inject.

Before I begin, I always make sure that I have the correct insulin by checking the name of the insulin on the label of my pen. If you use other injector pens, it is especially important to confirm you have the correct medicine.

KATHY: Also, check the label for the expiration date. Do not use your pen if it’s after the expiration date.

GAIL: First, make sure your hands are clean, and then pull off the pen cap. Take a look at the insulin inside the pen to see if it is clear.

KATHY: Don’t use the pen if the insulin looks cloudy, colored, or contains particles. If you see any of these, use a new pen.

GAIL: Next, wipe the rubber seal at the end of the pen with an alcohol swab. Now you are ready for the next step.

KATHY: Step 2: Attach a new needle

There are a few things to remember before we show you how to attach the needle. Do NOT reuse needles. Be sure to always use a new, sterile needle for each injection. This helps stop blocked needles, contamination, and infection.

Always use needles from BD (such as BD Ultra-Fine®), Ypsomed (such as Clickfine®) or Owen Mumford (such as Unifine® Pentips®).

GAIL: First, take a new needle and peel off the protective seal.

Hold the needle so it’s straight, and then screw it onto the pen. Be careful not to overtighten it.

Next, pull off the outer needle cap and put it to the side—you’ll need it after you have finished injecting.

Then pull off the inner needle cap and throw it away.

KATHY: Remember to be careful when you’re handling needles. You want to avoid injuring yourself with the needle, and also make sure that the needle stays sterile.

Step 3: Perform a safety test

Always do a safety test before each injection to make sure your pen and needle are working properly. This can help to make sure that you get the correct insulin dose.

GAIL: To begin, select 3 units by turning the dose selector until the dose pointer is at the mark between 2 and 4.

Then press the injection button all the way in. When insulin comes out of the needle tip, you know that the pen is working correctly.

If no insulin appears, you may need to repeat this step up to 3 times before seeing insulin.

KATHY: If no insulin comes out after the third time, the needle may be blocked. If this happens, simply change the needle and repeat the safety test.

If you have repeated the safety test with a new needle, but there still is no insulin coming out of the needle tip, do not use the pen. Use a new one.

Here are some other things to remember as you prepare for your injection. Do not use a syringe to remove insulin from your pen.

Also, you may see air bubbles in the insulin. This is normal; they will not harm you.

Step 4: Select the dose

GAIL: Your Toujeo® SoloStar® pen contains a total of 450 units of insulin.

You can select doses from 1 to 80 units in steps of 1 unit. Each pen contains more than 1 dose. You can see roughly how many units of insulin are left by looking at where the plunger is on the insulin scale.

Ask for help if you have any problems handling the pen, for example if you have problems with your eyesight.

KATHY: Before selecting a dose, first make sure there is a needle attached and the dose is set to 0. Do not select a dose or press the injection button without a needle attached. This may damage the pen.

GAIL: The dose window shows the amount of units selected. Even numbers are shown in line with the dose pointer. Odd numbers are shown as a line between even numbers.

To select your dose, turn the dose selector until the dose pointer lines up with your dose. If you turn past your dose, you can turn it back.

If there aren’t enough units in your pen to get your full dose, the dose selector will stop at the number of units left. If you can’t select your full prescribed dose, you can split the dose between two pens. Or, simply use a new pen.

KATHY: Step 5: Inject your dose

Toujeo® can be injected in three areas of your body.

Anywhere in your stomach area, except for a two-inch radius around the navel... the fatty tissue on the outer back area of your upper arm...

...or in your thighs. Avoid injecting too close to the bony area above your knees.

Remember, the injection site should be changed each time you inject.

Here are a few other guidelines you should follow when you inject.

Do not inject your insulin into a vein...

...rotate your injection sites as instructed by your doctor...

...never reuse needles... not use your pen if it is damaged or not working properly, and if you find it hard to press the injection button in, do not force it as this may break your pen.

GAIL: Once you’ve chosen an injection site, wipe the injection site with an alcohol swab. Then, push the needle into your skin as shown by your healthcare provider. Do not touch the injection button yet.

Next, place your thumb on the injection button, then press all the way in and hold. Don’t press at an angle, or your thumb could block the dose selector from turning.

Keep the injection button held in, and when you see “0” in the dose window, slowly count to 5. This will make sure you get your full dose.

After holding and slowly counting to 5, release the injection button. Then remove the needle from your skin.

KATHY: If you find it hard to press the button in, change the needle and then do a safety test like we showed you earlier in this video. If you still find it hard to press in, get a new pen. Do not use a syringe to remove insulin from your pen.

Step 6: How to remove and dispose of used needles, and then store your Toujeo® SoloStar® pen for future use.

After you’ve injected your dose, it’s time to remove the needle. Remember to take care when handling needles to prevent needle injury and cross-infection. Also, do not put the inner needle cap back on.

GAIL: To remove the needle, first grip the widest part of the outer needle cap. Keep the needle straight and guide it into the outer needle cap. Then push the cap firmly on. Be careful; the needle can puncture the cap if you guide it in at an angle.

Next, grip and squeeze the widest part of the outer needle cap, and then turn the pen several times with your other hand to remove the needle. If the needle does not come off at first, try again.

Once the needle is off, throw it away in a sharps puncture-resistant container. Be sure to only dispose of used needles in this type of container.

Your Sharps container can also be used to dispose of your pen when it is time to discard it.

For more information on the right containers you should use, visit www dot safe needle disposal dot org.

Finally, put the pen cap back on, but do not put the pen back in the refrigerator. We’ll go over how to store the pen next.

This completes the 6 steps to injecting and using the Toujeo® SoloStar® pen.

KATHY: Please refer to the Toujeo® Instructions for Use provided with your pen, if you have questions.

Finally, let’s talk about how to store your SoloStar® pen.

An opened Toujeo® SoloStar® pen should be stored at room temperature below 86 degrees Fahrenheit (30 degrees Celsius). Do not refrigerate an opened SoloStar® pen.

Keep out of direct heat and light.

Do not store your pen with the needle attached.

Store your pen with the pen cap on.

Discard 42 days after first use even if the pen still contains insulin.

An unopened Toujeo® SoloStar® pen should be stored in the refrigerator with the pen cap on at a temperature between 36 degrees Fahrenheit and 46 degrees Fahrenheit (2 degrees Celsius and 8 degrees Celsius) in the box it came in. Do not freeze new pens. Discard pens after the expiration date.

GAIL: Thanks for joining Kathy and I as we walked through how to use the Toujeo® SoloStar® pen. We hope that you found these instructions helpful.

KATHY: If you have any further questions about the Toujeo® SoloStar® pen or managing your diabetes, speak to your doctor, nurse, or pharmacist.

We will now present the full Important Safety Information for Toujeo®.

What is Toujeo® (insulin glargine injection) 300 Units/mL?

Prescription Toujeo® is a long-acting insulin used to control blood sugar in adults with diabetes mellitus.

  • Toujeo® contains 3 times as much insulin in 1 mL as standard insulin (100 Units/mL)
  • Toujeo® is not for use to treat diabetic ketoacidosis
  • Toujeo® should not be used in children

Important Safety Information for Toujeo® (insulin glargine injection) 300 Units/mL

Do not take Toujeo® if you have low blood sugar or if you are allergic to insulin or any of the ingredients in Toujeo®.

Do NOT reuse needles or share insulin pens even if the needle has been changed.

Before starting Toujeo®, tell your doctor about all your medical conditions, including if you have liver or kidney problems, if you are pregnant or planning to become pregnant or if you are breastfeeding or planning to breastfeed.

Heart failure can occur if you are taking insulin together with pills called TZDs (thiazolidinediones), even if you have never had heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Toujeo®. Your treatment with TZDs and Toujeo® may need to be changed or stopped by your doctor if you have new or worsening heart failure. Tell your doctor if you have any new or worsening symptoms, including:

  • Shortness of breath
  • Sudden weight gain
  • Swelling of your ankles or feet

Tell your doctor about all the medications you take, including OTC medicines, vitamins, supplements, and herbal supplements.

Toujeo® should be taken at the same time once a day. Test your blood sugar levels daily while using insulin, including Toujeo®. Do not change your dose or type of insulin without talking to your doctor. Verify that you have the correct insulin before each injection. Do NOT use a syringe to remove Toujeo® from your SoloStar® pen. Your dose for Toujeo® may be different from other insulins you have taken. Any change of insulin should be made cautiously and only under medical supervision.

Do NOT dilute or mix Toujeo® with any other insulin or solution. It will not work as intended and you may lose blood sugar control, which could be serious. Use Toujeo® only if the solution is clear and colorless with no particles visible.

While using Toujeo®, do not drive or operate heavy machinery until you know how Toujeo® affects you. Don’t drink alcohol or use medicines that contain alcohol.

The most common side effect of any insulin, including Toujeo®, is low blood sugar (hypoglycemia), which may be serious and life-threatening. Severe hypoglycemia may cause harm to your heart or brain. Symptoms of serious low blood sugar may include shaking, sweating, fast heartbeat, and blurred vision.

Toujeo® may cause severe allergic reactions that can lead to death. Get medical help right away if you have:

  • A rash over your whole body
  • Shortness of breath
  • Swelling of your face, tongue, or throat
  • Extreme drowsiness, dizziness, or confusion
  • Trouble breathing
  • Fast heartbeat
  • Sweating

Toujeo® may have additional side effects including swelling, weight gain, low potassium, and injection site reactions which may include change in fat tissue, skin thickening, redness, swelling, and itching.

Toujeo® SoloStar® is a disposable prefilled insulin pen. Talk to your doctor about proper injection technique and follow instructions in the Instruction Leaflet that comes with the pen.

Please see full Prescribing Information for Toujeo® provided at the link below.

Back to Video

Start your once-daily, long-acting insulin Toujeo treatment off right by learning how to use the Toujeo SoloStar® pen. This video walks you through what you need to know about using the Toujeo SoloStar pen.

“I like the small needle, the push button injection— and a dosing window I can actually see.”
―Gail, a real Toujeo patient

Is the Toujeo SoloStar pen easy
to use?
People said “yes”

At the end of a 4-week study, 95% of type 2 first-time insulin users rated the Toujeo SoloStar pen as easy to use.

All patients in the study were trained how to use the pen by their healthcare providers.

It is important to ask your healthcare provider how to use the pen before using it.

The redesigned Toujeo SoloStar prefilled pen is based on the award-winning design of the Lantus® (insulin glargine injection) 100 Units/mL SoloStar pen.

Toujeo® SoloStar® pen

The Toujeo SoloStar pen can stay 6 weeks out of the fridge after first use.

*The study compared Toujeo SoloStar, FlexPen®, and KwikPen® in a laboratory environment; doses were not delivered into tissue.

Once a day, every day

Toujeo is a long-acting insulin that should be taken once daily at the same time each day.
It releases gradually with no pronounced peak or wear-off between doses.

Dial in your recommended dose

Insulin first-timers:

Everybody's diabetes is different. Expect your starting dose to be adjusted over time. Often, it will be increased until your doctor working with you finds the Toujeo dose you need.

Already long-acting insulin users:

Expect to start at the same dose as your other long-acting insulin, and your doctor may adjust as necessary.

Having a routine
can help

Work with your doctor to pick a time that fits your schedule, and take Toujeo at that same time each day to help with blood sugar control around the clock. A good way to help remember is to find something that you already do at the same time each day. For example:


Right after your
morning walk


When your favorite
TV show starts


Before you go to bed


Get your own Coach to help you get started

You get lots of advice about diabetes. But how do you make sense of it all? Once you discuss your treatment plan with your doctor, Toujeo COACH can help. Whether you're just beginning long-acting insulin, or are already on it, it's nice to have someone to turn to. And of course, it's at no cost to you. You need a Toujeo prescription to get started on COACH.

Get only the support you want, the way you want it

One size does not fit all. With Toujeo COACH, you decide how you want your Nurse Coach  to communicate with you. You can receive calls, e-mails, or texts.

Your own Nurse Coach

Once you sign up, your Nurse Coach will reach out and be your regular contact. It’s all about helping you work toward better managing your diabetes based on your doctor's treatment plan.

Tips tailored for you

Want tips? Your Nurse Coach can help. Topics include: meal planning, blood sugar testing, how to inject insulin, medication reminders, and more.

Once you have a prescription, you can sign up

Everyone starting Toujeo can get a Coach.

Most common and Serious side effects

When taking any medication, it's important to understand how it might affect your body, and Toujeo is no different. Before starting Toujeo, talk to your doctor about all the possible side effects.

For all insulins, including Toujeo, the most common side effect is hypoglycemia. Ask your doctor about the signs and symptoms of hypoglycemia, how to monitor your blood sugar, and what to do if you have a hypoglycemic event.

Toujeo may cause serious side effects including severe allergic reactions. Get medical help right away if you have:

  • A rash over your whole body
  • Extreme drowsiness, dizziness, or confusion
  • Shortness of breath
  • Trouble breathing
  • Swelling of your face, tongue, or throat
  • Fast heartbeat

These are not all the possible side effects of Toujeo. Talk with your doctor about possible side effects.
For more detailed information, see the full Important Safety Information and full Prescribing Information.

Also keep in mind

Also keep in mind

Do not use a syringe to remove Toujeo from your SoloStar disposable prefilled pen. Never reuse needles or share insulin pens even if the needle has been changed.

FAQs: Questions people ask about Toujeo

If you’re like most people, you have questions. Let us break down the answers to some of the questions most often asked about diabetes—and Toujeo.

Your body and your diabetes change over time, and your treatment plan might have to also. If diet and exercise aren’t enough, talk with your doctor to see if it may be time for insulin.

Watch video

Long-acting insulin is designed to work like your body’s natural insulin production between meals and overnight to help control blood sugar.

Get more facts

Toujeo may be an important step toward blood sugar control. Its release is slow and continuous with no peaks or wear-offs between doses. Toujeo can help provide blood sugar levels within the ADA target zone (80-130 mg/dL) around the clock. Toujeo should be taken once daily at the same time each day.

Give me details

You should take once-daily, long-acting Toujeo at the same time each day. It may help improve your blood sugar control around the clock. That’s why it’s important to set up a daily routine and to work with your doctor to choose a time that fits best with your schedule.

Create a routine

Yes, but your doctor will determine what medications are right for you. Talk with your doctor about the medications and supplements you take, especially those called thiazolidinediones or TZDs because they can change how insulin works.

Ask your doctor about any adjustments that need to be made while taking once-daily, Toujeo.

About your dose

Simply put: 1 unit of once-daily, long-acting Toujeo has the same amount of insulin as 1 unit of Lantus. After starting, your doctor may recommend increasing your dose to help you work towards your blood sugar goals.

Switching from Lantus

Maybe. Work closely with your doctor to see if any increase is needed.

About your dose

For all insulins, including Toujeo®, the most common side effect is hypoglycemia. Ask your doctor about the signs and symptoms of hypoglycemia, how to monitor your blood sugar, and what to do if you have a hypoglycemic event.

More about side effects


If you're new to Toujeo, get your first 3 copays for $0*

then get your next 12 refills for $10 each.

*See full offer terms, including limitations and eligibility restrictions


Get questions
to ask your doctor

Be prepared for your next doctor visit with our downloadable thought starters.



Are you and your doctor ready to make a move to Toujeo?

If eligible, you'll get a $10* copay on the Toujeo SoloStar® pen, even if it’s not covered by your insurance.